вот код для звонка в скайп с vb.net, включая декларацию.
Imports SKYPE4COMLib
Public class form 1
Public WithEvents skype As New SKYPE4COMLib.Skype
Private Sub Form1_Load(sender As Object, e As EventArgs) Handles MyBase.Load
'check if the skype client is running
If Not skype.Client.IsRunning Then
skype.Client.Start()
End If
end sub
'use a button or other control to place a call to the test account of skype
Private Sub Button1_Click(sender As Object, e As EventArgs) Handles Button1.Click
skype.PlaceCall("echo123")
End Sub
чтобы позвонить кому-то другому, просто замените echo123, не забывайте "кавычки"