изменение% 2B на + API прошло
import requests
import datetime
import hmac
import hashlib
import base64
username = "example_username"
apiKey= 'example_apiKey'
now = datetime.datetime.now()
nowTime = now.strftime('%a, %d %b %Y %H:%M:%S GMT')
nowTime_bytes = bytes(nowTime, encoding='utf-8')
value = hmac.new(apiKey, nowTime_bytes, hashlib.sha1).digest()
token = base64.b64encode(value).rstrip()
headers = {"Accept": "application/json","Date": nowTime}
payload= {'datefrom':'2017-11-07T00:00:00+08:00','dateto':'2017-11-07T00:15:00+08:00','type': 'fiveminutes'}
xml = '<?xml version="1.0" encoding="utf-8"?> <domain-list><domain-name>www.example1.com</domain-name></domain-list>'
r = requests.post(url, headers=headers, auth=(username, token), data=xml,params=payload)
print (r)