Не используйте "A:A"
Установите Range
, Autofilter
, затем l oop через каждую ячейку в диапазоне и очистите.
Dim rng As Range: Set rng = ThisWorkbook.Sheets("Sheet1").Range("A2", Range("A" & Rows.Count).End(xlUp))
With rng
.AutoFilter 1, "x"
For Each cel In rng
cel.Clear
Next cel
End With