Вы можете использовать split () строки, как показано ниже:
lst = [("['106.52.116.101']", 1), ("['45.136.108.85']", 1)]
print(lst)
new_lst = [(first.split('\'')[1], sec)for first, sec in lst]
print(new_lst)
output
[("['106.52.116.101']", 1), ("['45.136.108.85']", 1)]
[('106.52.116.101', 1), ('45.136.108.85', 1)]