Я предполагаю, что вы обрабатываете событие DataList
ItemCommand , устанавливая свойство Button CommandName .
Sub Item_Command(sender As Object, e As DataListCommandEventArgs)Handles DataList1.ItemCommand
' What command was triggered?
If e.CommandName = "YourCommandName" Then
' Get the Label in the DataListItem of the clicked button
Dim lbl = DirectCast(e.Item.FindControl("Label1"), Label)
Dim labelText = lbl.Text
End If
End Sub