Вот пример того, как достичь своей цели:
В наборе Web.config
<appSettings>
<add key="ValidationSettings:UnobtrusiveValidationMode" value="None"/>
В aspx
<telerik:RadMaskedTextBox Mask="(###) ###-#### ext. #####" RenderMode="Lightweight" ID="RadMaskedTextBox1" runat="server" EmptyMessage="Enter username"></telerik:RadMaskedTextBox>
<asp:RequiredFieldValidator ID="RequiredFieldValidator1" runat="server" Text="*" ControlToValidate="RadMaskedTextBox1"></asp:RequiredFieldValidator>
<asp:Button ID="Button1" runat="server" Text="PostBack" />