Это может помочь вам начать:
Sub Tester()
Dim oCht As Excel.Chart, s As Series
Dim x As Integer, i As Integer
Dim oldColor As Long
Set oCht = ActiveSheet.ChartObjects("Chart 1").Chart
For x = 1 To oCht.SeriesCollection.Count
Set s = oCht.SeriesCollection(x)
For i = 1 To s.Points.Count
With s.Points(i).Interior
oldColor = .Color
.Color = vbRed
DoEvents
Application.Wait Now + TimeSerial(0, 0, 2)
.Color = oldColor
DoEvents
End With
Next i
Next x
End Sub