с Python 2.6 вы можете использовать библиотеку запросов, вот фрагмент, извлеченный из документации :
>>> url = 'http://httpbin.org/post'
>>> files = {'report.xls': open('report.xls', 'rb')}
>>> r = requests.post(url, files=files)
>>> r.text
{
"origin": "179.13.100.4",
"files": {
"report.xls": "<censored...binary...data>"
},
"form": {},
"url": "http://httpbin.org/post",
"args": {},
"headers": {
"Content-Length": "3196",
"Accept-Encoding": "identity, deflate, compress, gzip",
"Accept": "*/*",
"User-Agent": "python-requests/0.8.0",
"Host": "httpbin.org:80",
"Content-Type": "multipart/form-data; boundary=127.0.0.1.502.21746.1321131593.786.1"
},
"data": ""
}